NAD⁺ (Nicotinamide Adenine Dinucleotide, Oxidized Form)

NAD⁺ is a vital pyridine nucleotide coenzyme involved in over 500 cellular reactions related to energy metabolism, mitochondrial function, and DNA repair. It serves as an electron carrier in redox reactions and a substrate for sirtuins and PARP enzymes—central regulators of aging and metabolic health.

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Key Research Features

  • Mitochondrial cofactor: Essential for oxidative phosphorylation and ATP production.
  • Sirtuin activation: Supports studies on SIRT1–SIRT7–mediated gene regulation and metabolic control.
  • DNA-repair substrate: Provides ADP-ribose units for PARP-dependent repair mechanisms.
  • NAD⁺/NADH ratio modeling: Quantifies cellular redox balance and metabolic flux.
  • Neuroprotection and energy restoration: Evaluated in neuronal and ischemic stress models. Metabolic synergy: Frequently co-studied with MOTS-c, 5-Amino-1MQ, and Glutathione in aging-pathway research.

Research Applications

  • Telomere and genomic-stability research
  • Neuroendocrine and circadian-rhythm studies
  • DNA-damage and oxidative-stress assays
  • Aging-pathway and epigenetic regulation models

Research Classification

For laboratory research only. Not for human or animal use.

Storage & Handling

Store –20 °C (dry). Reconstitute under sterile conditions. Use within standard stability limits after reconstitution

All products offered by PureGeniX Wellness are intended for research and educational purposes only. These compounds have not been evaluated or approved by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Information provided on this site is for research, education, and informational purposes only and should not be interpreted as medical advice. Always consult your licensed healthcare provider regarding any medical concerns or before starting any wellness protocol.

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