ARA-290 (Innate Repair Receptor Agonist / Erythropoietin-Derived Peptide)

ARA-290 (Innate Repair Receptor Agonist / Erythropoietin-Derived Peptide)

ARA-290 is an 11-amino-acid peptide derived from erythropoietin (EPO) that selectively activates the innate repair receptor (IRR) without stimulating erythropoiesis. It is studied for its tissue-protective, anti-inflammatory, and neuro-repair properties in vascular and metabolic models.

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Key Research Features

IRR-selective action: Binds the EPOR/CD131 receptor complex to trigger cytoprotective signaling.
Non-erythropoietic: Lacks hematopoietic stimulation, allowing use in metabolic and inflammation studies.
Neuro- and endothelium-protective: Demonstrated preservation of nerve function and vascular integrity.
Anti-inflammatory signaling: Inhibits NF-κB activation and reduces TNF-α and IL-1β expression.
Microvascular restoration: Supports endothelial-cell survival and capillary repair in ischemia models.
Mitochondrial preservation: Reduces oxidative stress and apoptosis following tissue injury.

Research Applications

Neuropathy and vascular-repair studies
Inflammatory and ischemia-reperfusion models
Cytoprotection and mitochondrial-function assays
Erythropoietin-receptor and cytokine-modulation research

Research Classification

For laboratory research only. Not for human or animal use.

Storage & Handling

Store –20 °C (dry). Reconstitute under sterile conditions. Use within standard stability limits after reconstitution

All products offered by PureGeniX Wellness are intended for research and educational purposes only. These compounds have not been evaluated or approved by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Information provided on this site is for research, education, and informational purposes only and should not be interpreted as medical advice. Always consult your licensed healthcare provider regarding any medical concerns or before starting any wellness protocol.

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$50

Available Sizes

10 mg

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